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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Canine discoid lupus erythematosus ： ウィキペディア英語版 Canine discoid lupus erythematosus Discoid lupus erythematosus (DLE) is an uncommon autoimmune disease of the basal cell layer of the skin. It occurs in humans〔( American Osteopathic College of Dermatology, "Discoid Lupus Erythematosus" ).〕 and cats, more frequently occurring in dogs. It does not progress to systemic lupus erythematosus (SLE) in dogs. SLE can also have skin symptoms, but it appears that the two are either separate diseases or DLE is a mild form of SLE. DLE in dogs differs from SLE in humans in that plasma cells predominate histologically instead of T lymphocytes. Because worsening of symptoms occurs with increased ultraviolet light exposure, sun exposure most likely plays a role in DLE, although certain breeds (see below) are predisposed. After pemphigus foliaceus, DLE is the second most common autoimmune skin disease in dogs. ==Symptoms== The most common initial symptom is scaling and loss of pigment on the nose. This is found in up to 90 percent of affected dogs.〔 The surface of the nose becomes smooth gray, and ulcerated, instead of the normal black cobblestone texture. Over time the lips, the skin around the eyes, the ears, and the genitals may become involved. Lesions may progress to ulceration and lead to tissue destruction. DLE is often worse in summer due to increased sun exposure. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Canine discoid lupus erythematosus」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.